Take a journey down the mightiest river on the planet, home to more than 5000 different species of fish and hundreds of thousands of different species of plant life. Join tribal shaman, Mamani, and American ethnobotanist, Dr. Mark Plotkin, on their search for the medicinal qualities of native plants. Here, Western medical science meets the myth and magic of Indian shamanism, a very real collaboration that can bring cures to diseases not yet conquered.